Effects of chlorogenic acid and its metabolites on spontaneous locomotor activity in mice.
نویسندگان
چکیده
Chlorogenic acid possessed a weak caffeine-like psychostimulant property when assessed for its effect on spontaneous locomotor activity in mice. In the evaluation of the effects for the major metabolites of chlorogenic acid which were detected upon incubation with rat feces and/or excreted in urine after oral administration to rats, caffeic and m-coumaric acids were found to be the principal active metabolites, while the others contributed little to this caffeine-like psychostimulant activity.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 70 10 شماره
صفحات -
تاریخ انتشار 2006